TargetMol

Sch 47896

Product Code:
 
TAR-T28721
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28721-5mg5mg£850.00
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TAR-T28721-50mg50mg£1,661.00
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Quantity:
TAR-T28721-100mg100mg£2,079.00
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Further Information

Bioactivity:
Sch 47896 is an inhibitor of neutral metalloendopeptidase (NEP).
CAS:
142621-29-2
Formula:
C22H26N2O7
Molecular Weight:
430.457
Purity:
0.98
SMILES:
O[C@@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)N[C@@H](CCc1ccc(O)cc1)C(O)=O

References

1. Jandeleit-Dahm K, Burrell LM, Kanazawa M, Casley D, Jackson B, Johnston CI. Effects of neutral endopeptidase inhibition in the rat remnant kidney model. Kidney Blood Press Res. 1998;21(6):419-24. PubMed PMID: 9933826. 2. Yoshida K, Kanazawa M, Casley DJ, Katopothis A, Johnston CI. Inhibition of kidney neutral endopeptidase after administration of the neutral endopeptidase inhibitor candoxatril: quantitation by autoradiography. J Cardiovasc Pharmacol. 1998 Nov;32(5):702-8. PubMed PMID: 9821842. 3. Kanazawa M, Yasujima M, Kohzuki M, Abe K. [Activity and localization of neutral metalloendopeptidase (EC 3.4.24.11) (NEP), the degradative enzyme for atrial natriuretic peptide (ANP), in rat kidney]. Nihon Jinzo Gakkai Shi. 1994 Jul;36(7):791-9. Japanese. PubMed PMID: 8072216. 4. Kanazawa M, Casley DJ, Sybertz EJ, Haslanger MF, Johnston CI. Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor. J Pharmacol Exp Ther. 1992 Jun;261(3):1231-7. PubMed PMID: 1534841.