TargetMol

SC-22716

Product Code:
 
TAR-T28698
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28698-5mg5mg£850.00
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Quantity:
TAR-T28698-50mg50mg£1,661.00
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Quantity:
TAR-T28698-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
SC-22716 is a cell-permeable leukotriene A4 (LTA4) hydrolase inhibitor which suppresses the production of LTB4. SC-22716 is implicated in the pathogenesis of many diseases including inflammatory bowel disease and psoriasis.
CAS:
262451-89-8
Formula:
C18H21NO
Molecular Weight:
267.372
Purity:
0.98
SMILES:
C(CN1CCCC1)Oc1ccc(cc1)-c1ccccc1

References

1. Penning TD, Chandrakumar NS, Chen BB, Chen HY, Desai BN, Djuric SW, Docter SH, Gasiecki AF, Haack RA, Miyashiro JM, Russell MA, Yu SS, Corley DG, Durley RC, Kilpatrick BF, Parnas BL, Askonas LJ, Gierse JK, Harding EI, Highkin MK, Kachur JF, Kim SH, Krivi GG, Villani-Price D, Pyla EY, Smith WG. Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase. J Med Chem. 2000 Feb 24;43(4):721-35. PubMed PMID: 10691697.