TargetMol

SB357134

Product Code:
 
TAR-T28689
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28689-5mg5mg£850.00
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Quantity:
TAR-T28689-50mg50mg£1,661.00
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Quantity:
TAR-T28689-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB357134 is a potent, selective and orally active antagonist of 5-HT6 receptor and shows nootropic effects in animal studies.
CAS:
219963-52-7
Formula:
C17H18Br2FN3O3S
Molecular Weight:
523.22
Purity:
0.98
SMILES:
COc1ccc(cc1N1CCNCC1)S(=O)(=O)Nc1cc(Br)cc(F)c1Br

References

1. Meneses A. Do serotonin(1-7) receptors modulate short and long-term memory? Neurobiol Learn Mem. 2007 May;87(4):561-72. Epub 2007 Jan 16. PubMed PMID: 17224282. 2. Marcos B, Gil-Bea FJ, Hirst WD, Garc?a-Alloza M, Ram?rez MJ. Lack of localization of 5-HT6 receptors on cholinergic neurons: implication of multiple neurotransmitter systems in 5-HT6 receptor-mediated acetylcholine release. Eur J Neurosci. 2006 Sep;24(5):1299-306. PubMed PMID: 16987217. 3. Perez-Garc?a G, Meneses A. Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task. Pharmacol Biochem Behav. 2005 Jul;81(3):673-82. PubMed PMID: 15964617. 4. Russell MG, Dias R. Memories are made of this (perhaps): a review of serotonin 5-HT(6) receptor ligands and their biological functions. Curr Top Med Chem. 2002 Jun;2(6):643-54. Review. PubMed PMID: 12052198.