TargetMol

SB 210661

Product Code:
 
TAR-T28674
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T28674-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB 210661 is a potent and selective 5-lipoxygenase inhibitor.
CAS:
162750-10-9
Formula:
C16H14F2N2O4
Molecular Weight:
336.295
Purity:
0.98
SMILES:
NC(=O)N(O)[C@@H]1COc2cc(OCc3c(F)cccc3F)ccc12

References

1. Mey J, Babiuk RP, Clugston R, Zhang W, Greer JJ. Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents. Am J Pathol. 2003 Feb;162(2):673-9. PubMed PMID: 12547725; PubMed Central PMCID: PMC1851155. 2. Solomon HM, Wier PJ, Johnson CM, Posobiec LM, Rendemonti JE, Rumberger DF. Benzofuranyl ureas with potent cardiovascular teratogenicity in rats. Teratology. 2000 Mar;61(3):211-21. PubMed PMID: 10661911. 3. Salmon M, Walsh DA, Huang TJ, Barnes PJ, Leonard TB, Hay DW, Chung KF. Involvement of cysteinyl leukotrienes in airway smooth muscle cell DNA synthesis after repeated allergen exposure in sensitized Brown Norway rats. Br J Pharmacol. 1999 Jul;127(5):1151-8. PubMed PMID: 10455261; PubMed Central PMCID: PMC1566132. 4. Hisada T, Salmon M, Nasuhara Y, Chung KF. Cysteinyl-leukotrienes partly mediate eotaxin-induced bronchial hyperresponsiveness and eosinophilia in IL-5 transgenic mice. Am J Respir Crit Care Med. 1999 Aug;160(2):571-5. PubMed PMID: 10430730.