TargetMol

Ro 23-7637

Product Code:
 
TAR-T28573
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28573-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28573-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28573-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Ro 23-7637 is a drug may have potent to treat metabolic diseases.
CAS:
107071-66-9
Formula:
C33H40N2O
Molecular Weight:
480.696
Purity:
0.98
SMILES:
O=C(CCCCCCCCc1cccnc1)N1CCC(CC1)C=C(c1ccccc1)c1ccccc1

References

1. White JD, Blakemore PR, Milicevic S, Choudhry SC, Cupano J, Serico L. Conversion of carbamates to amidosulfones and amides. Synthesis of the [14C]-labeled antiobesity agent Ro23-7637. Org Lett. 2002 May 16;4(10):1803-6. PubMed PMID: 12000303. 2. Ghosal A, Satoh H, Thomas PE, Bush E, Moore D. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450. Drug Metab Dispos. 1996 Sep;24(9):940-7. PubMed PMID: 8886602. 3. Campfield LA, Smith FJ, Mackie G, Tenenbaum R, Sassano ML, Mullin J, Kaiser K, Kierstead RW. Insulin normalization as an approach to the pharmacological treatment of obesity. Obes Res. 1995 Nov;3 Suppl 4:591S-603S. PubMed PMID: 8697062. 4. Szuna AJ, Mulligan TE, Mico BA, Blain RW. Determination of Ro 23-7637 in dog plasma by multidimensional ion-exchange-reversed-phase high-performance liquid chromatography with ultraviolet detection. J Chromatogr. 1993 Jul 2;616(2):297-303. PubMed PMID: 8376510.