TargetMol

Ro 17-1812

Product Code:
 
TAR-T28561
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28561-5mg5mg£850.00
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TAR-T28561-50mg50mg£1,661.00
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Quantity:
TAR-T28561-100mg100mg£2,079.00
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  • Further Information
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Further Information

Bioactivity:
Ro 17-1812 is a partial agonist of benzodiazepine receptor.
CAS:
90450-01-4
Formula:
C18H16ClN3O3
Molecular Weight:
357.79
Purity:
0.98
SMILES:
[H][C@@]12CCN1C(=O)c1c(Cl)cccc1-n1cnc(C(=O)OCC3CC3)c21

References

1. Cooper SJ, Green AE. The benzodiazepine receptor partial agonists, bretazenil (Ro 16-6028) and Ro 17-1812, affect saccharin preference and quinine aversion in the rat. Behav Pharmacol. 1993 Feb;4(1):81-85. PubMed PMID: 11224174. 2. Feely M, Boyland P, Picardo A, Cox A, Gent JP. Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812. Eur J Pharmacol. 1989 May 19;164(2):377-80. PubMed PMID: 2759183. 3. Potier MC, Prado de Carvalho L, Venault P, Chapouthier G, Rossier J. Demonstration of the partial agonist profiles of Ro 16-6028 and Ro 17-1812 in mice in vivo. Eur J Pharmacol. 1988 Oct 26;156(1):169-72. PubMed PMID: 2850207. 4. Saletu B, Gr?nberger J, Linzmayer L. Early clinical pharmacological trials with a novel partial benzodiazepine agonist/antagonist Ro 17-1812 using pharmaco-EEG and psychometry. Methods Find Exp Clin Pharmacol. 1986 Jun;8(6):373-89. PubMed PMID: 3736281.