TargetMol

Ro 14-7437

Product Code:
 
TAR-T28556
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28556-5mg5mg£850.00
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TAR-T28556-50mg50mg£1,661.00
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Quantity:
TAR-T28556-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ro 14-7437 is an antagonist of GABA-benzodiazepine receptor.
CAS:
78756-03-3
Formula:
C15H15N3O3
Molecular Weight:
285.303
Purity:
0.98
SMILES:
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1ccccc-21

References

1. Harris BD, Moody EJ, Gu ZQ, Skolnick P. Contribution of "diazepam-insensitive" GABAA receptors to the alcohol antagonist properties of Ro 15-4513 and related imidazobenzodiazepines. Pharmacol Biochem Behav. 1995 Sep;52(1):113-8. PubMed PMID: 7501652. 2. P?sp?k A, Herneth A, Steindl P, Ferenci P. Hepatic encephalopathy in rats with thioacetamide-induced acute liver failure is not mediated by endogenous benzodiazepines. Gastroenterology. 1993 Sep;105(3):851-7. PubMed PMID: 8359654. 3. Basile AS, Gammal SH, Mullen KD, Jones EA, Skolnick P. Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy. J Neurosci. 1988 Jul;8(7):2414-21. PubMed PMID: 2854841. 4. Laurent JP. [Pharmacologic bases of the action of benzodiazepine ligands]. Rev Med Suisse Romande. 1987 Sep;107(9):711-5. Review. French. PubMed PMID: 2827289.