TargetMol

Ro 13-3978

Product Code:
 
TAR-T28555
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28555-5mg5mg£850.00
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TAR-T28555-50mg50mg£1,661.00
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Quantity:
TAR-T28555-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
RO13-3978 is a broad-spectrum antischistosomal. Ro 13-3978 has excellent antischistosomal properties in vivo.
CAS:
70842-04-5
Formula:
C12H10F4N2O2
Molecular Weight:
290.218
Purity:
0.98
SMILES:
CC1(C)NC(=O)N(C1=O)c1ccc(F)c(c1)C(F)(F)F

References

1. Keiser J, Panic G, Vargas M, Wang C, Dong Y, Gautam N, Vennerstrom JL. Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal. J Antimicrob Chemother. 2015;70(6):1788-97. doi: 10.1093/jac/dkv016. PubMed PMID: 25691324; PubMed Central PMCID: PMC4462663. 2. Wang C, Zhao Q, Min J, Muniyan S, Vargas M, Wang X, Dong Y, Guy RK, Lin MF, Keiser J, Vennerstrom JL. Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978. Am J Trop Med Hyg. 2014 Jun;90(6):1156-8. doi: 10.4269/ajtmh.14-0029. PubMed PMID: 24686741; PubMed Central PMCID: PMC4047746. 3. Forget E, F?lix H, Notteghem MJ, L?ger N. [Efficacy of schistosomicide derivatives, appreciation with electronic microscopy experimental model (author's transl)]. Bull Soc Pathol Exot Filiales. 1982 Mar-Apr;75(2):192-200. French. PubMed PMID: 6809349.