TargetMol

ONO-1603

Product Code:
 
TAR-T28246
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28246-5mg5mg£850.00
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TAR-T28246-50mg50mg£1,661.00
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Quantity:
TAR-T28246-100mg100mg£2,079.00
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Further Information

Bioactivity:
ONO-1603, a prolyl endopeptidase inhibitor, is used potentially for the treatment of Alzheimer's disease.
CAS:
117427-00-6
Formula:
C16H19ClN2O3
Molecular Weight:
322.79
Purity:
0.98
SMILES:
Clc1ccc(CNC(=O)CCC(=O)N2CCC[C@H]2C=O)cc1

References

1. Katsube N, Sunaga K, Aishita H, Chuang DM, Ishitani R. ONO-1603, a potential antidementia drug, delays age-induced apoptosis and suppresses overexpression of glyceraldehyde-3-phosphate dehydrogenase in cultured central nervous system neurons. J Pharmacol Exp Ther. 1999 Jan;288(1):6-13. PubMed PMID: 9862746. 2. Katsube N, Sunaga K, Chuang DM, Ishitani R. ONO-1603, a potential antidementia drug, shows neuroprotective effects and increases m3-muscarinic receptor mRNA levels in differentiating rat cerebellar granule neurons. Neurosci Lett. 1996 Aug 23;214(2-3):151-4. PubMed PMID: 8878106.