TargetMol

NSC156529

Product Code:
 
TAR-T28203
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28203-5mg5mg£1,332.00
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Quantity:
TAR-T28203-50mg50mg£2,625.00
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Quantity:
TAR-T28203-100mg100mg£3,524.00
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This product comes from: United States.
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Further Information

Bioactivity:
NSC156529 downregulates AKT1 signaling. NSC156529 efficiently decreases the proliferation of human cancer cells in vitro, and substantially inhibits the growth of prostate tumor xenografts in vivo.
CAS:
41134-88-7
Formula:
C28H21ClS2
Molecular Weight:
457.05
Purity:
0.98
SMILES:
[Cl-].Cc1c2cccc3[S+](Cc(c23)c2c(Sc3ccccc3)cccc12)c1ccccc1

References

1. M?emets-Allas K, Belit?kin D, Jaks V. The inhibition of Akt-Pdpk1 interaction efficiently suppresses the growth of murine primary liver tumor cells. Biochem Biophys Res Commun. 2016 May 20;474(1):118-125. doi: 10.1016/j.bbrc.2016.04.082. Epub 2016 Apr 19. PubMed PMID: 27103434. 2. M?emets-Allas K, Viil J, Jaks V. A Novel Inhibitor of AKT1-PDPK1 Interaction Efficiently Suppresses the Activity of AKT Pathway and Restricts Tumor Growth In Vivo. Mol Cancer Ther. 2015 Nov;14(11):2486-96. doi: 10.1158/1535-7163.MCT-15-0281. Epub 2015 Aug 20. PubMed PMID: 26294745.