TargetMol

NS5818

Product Code:
 
TAR-T28198
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28198-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28198-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28198-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NS5818 inhibits ClC.
CAS:
674299-39-9
Formula:
C23H19Cl2N7O2
Molecular Weight:
496.35
Purity:
0.98
SMILES:
CN(C)C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cc(Cl)cc(Cl)c2)cc1-c1nn[nH]n1

References

1. Schulz P, Werner J, Stauber T, Henriksen K, Fendler K. The G215R mutation in the Cl-/H+-antiporter ClC-7 found in ADO II osteopetrosis does not abolish function but causes a severe trafficking defect. PLoS One. 2010 Sep 7;5(9):e12585. doi: 10.1371/journal.pone.0012585. PubMed PMID: 20830208; PubMed Central PMCID: PMC2935355. 2. Karsdal MA, Henriksen K, S?rensen MG, Gram J, Schaller S, Dziegiel MH, Heegaard AM, Christophersen P, Martin TJ, Christiansen C, Bollerslev J. Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. Am J Pathol. 2005 Feb;166(2):467-76. PubMed PMID: 15681830; PubMed Central PMCID: PMC1602325.