TargetMol

Nizofenone

Product Code:
 
TAR-T28176
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28176-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28176-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28176-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Nizofenone, a thromboxane A2 (TXA2) biosynthesis inhibitor, is used as a neuroprotective drug and used to treat stroke.
CAS:
54533-85-6
Formula:
C21H21ClN4O3
Molecular Weight:
412.87
Purity:
0.98
SMILES:
CCN(CC)Cc1nccn1-c1ccc(cc1C(=O)c1ccccc1Cl)[N+]([O-])=O

References

1. Liu Y, Zhuang X, Gou L, Ling X, Tian X, Liu L, Zheng Y, Zhang L, Yin X. Protective effects of nizofenone administration on the cognitive impairments induced by chronic restraint stress in mice. Pharmacol Biochem Behav. 2013 Jan;103(3):474-80. doi: 10.1016/j.pbb.2012.09.009. Epub 2012 Sep 28. PubMed PMID: 23026061. 2. Nakamura T, Tsumagari T. [Effects of nizofenone on experimental arrhythmia in dogs]. Nihon Yakurigaku Zasshi. 1984 Nov;84(5):441-51. Japanese. PubMed PMID: 6097519. 3. Miura Y, Inui J, Nakamura T. [Effects of nizofenone on the action potential of guinea-pig papillary muscle and S-A node and dog Purkinje fibers]. Nihon Yakurigaku Zasshi. 1985 Mar;85(3):159-65. Japanese. PubMed PMID: 4007706. 4. Saito I, Asano T, Ochiai C, Takakura K, Tamura A, Sano K. A double-blind clinical evaluation of the effect of Nizofenone (Y-9179) on delayed ischemic neurological deficits following aneurysmal rupture. Neurol Res. 1983;5(4):29-47. PubMed PMID: 6149485.