TargetMol

Naftazone

Product Code:
 
TAR-T28128
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28128-5mg5mg£850.00
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TAR-T28128-50mg50mg£1,661.00
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Quantity:
TAR-T28128-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Naftazone is a vasoprotectant drug used for hemostasis. Naftazone is shown to accelerate human saphenous vein endothelial cell proliferation in vitro at concentrations which did not alter the hemostatic balance.
CAS:
15687-37-3
Formula:
C11H9N3O2
Molecular Weight:
215.212
Purity:
0.98
SMILES:
NC(=O)NN=C1/C=Cc2ccccc2C1=O

References

1. Rascol O, Ferreira J, N?gre-Pages L, Perez-Lloret S, Lacomblez L, Galitzky M, Lemari? JC, Corvol JC, Brotchie JM, Bossi L. A proof-of-concept, randomized, placebo-controlled, multiple cross-overs (n-of-1) study of naftazone in Parkinson's disease. Fundam Clin Pharmacol. 2012 Aug;26(4):557-64. doi: 10.1111/j.1472-8206.2011.00951.x. Epub 2011 May 18. PubMed PMID: 21585523. 2. Jeon DG, Song JG, Kim SK, Kim J. Epidural hematoma after thoracic epidural analgesia in a patient treated with ketorolac, mefenamic acid, and naftazone: a case report. Korean J Anesthesiol. 2014 Mar;66(3):240-3. doi: 10.4097/kjae.2014.66.3.240. Epub 2014 Mar 28. PubMed PMID: 24729848; PubMed Central PMCID: PMC3983422. 3. Walash MI, Belal F, El-Enany N, Eid M, El-Shaheny RN. Stability-indicating HPLC method for determination of naftazone in tablets. Application to degradation kinetics and content uniformity testing. J Chromatogr Sci. 2011 Aug;49(7):495-501. PubMed PMID: 21801479. 4. Durand P, Bloy C, Peltier-Pujol F, Blache D. In-vitro and ex-vivo inhibition of blood platelet aggregation by naftazone. J Pharm Pharmacol. 1996 Jun;48(6):566-72. PubMed PMID: 8832488.