TargetMol

MAC173979

Product Code:
 
TAR-T27972
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27972-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27972-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27972-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MAC173979 inhibits E. coli de novo PABA biosynthesis and growth.
CAS:
41501-64-8
Formula:
C9H5Cl2NO3
Molecular Weight:
246.04
Purity:
0.98
SMILES:
[O-][N+](=O)c1cccc(c1)C(=O)C=C(Cl)Cl

References

1. Thiede JM, Kordus SL, Turman BJ, Buonomo JA, Aldrich CC, Minato Y, Baughn AD. Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates. Sci Rep. 2016 Dec 1;6:38083. doi: 10.1038/srep38083. PubMed PMID: 27905500; PubMed Central PMCID: PMC5131483. 2. Zlitni S, Ferruccio LF, Brown ED. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9(12):796-804. doi: 10.1038/nchembio.1361. Epub 2013 Oct 13. PubMed PMID: 24121552; PubMed Central PMCID: PMC3970981.