TargetMol

LY392098

Product Code:
 
TAR-T27951
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T27951-1mg1mg£149.00
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TAR-T27951-2mg2mg£187.00
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TAR-T27951-5mg5mg£269.00
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TAR-T27951-1mL1 mL * 10 mM (in DMSO)£279.00
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TAR-T27951-10mg10mg£389.00
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TAR-T27951-25mg25mg£603.00
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Quantity:
TAR-T27951-50mg50mg£830.00
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TAR-T27951-100mg100mg£1,099.00
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Quantity:
TAR-T27951-500mg500mg£2,135.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
LY392098 is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
CAS:
211311-39-6
Formula:
C18H22FNO2S
Molecular Weight:
335.44
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.9985
SMILES:
O=S(=O)(NCC(C=1C=CC(=CC1)C=2C=CC=CC2F)C)C(C)C
Target:
GluR; iGluR

References

1. O'Neill MJ, Witkin JM. AMPA receptor potentiators: application for depression and Parkinson's disease. Curr Drug Targets. 2007 May;8(5):603-20. Review. 2. Farley S, et al. Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm. Int J Neuropsychopharmacol. 2010 Oct;13(9):1207-18. 3. Kasper Harps?e, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26(5):874-83.