TargetMol

LY191704

Product Code:
 
TAR-T27889
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27889-5mg5mg£850.00
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Quantity:
TAR-T27889-50mg50mg£1,661.00
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Quantity:
TAR-T27889-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
LY 191704 is a 5α-reductase type 1 inhibitor.
CAS:
146117-78-4
Formula:
C14H16ClNO
Molecular Weight:
249.74
Purity:
0.98
SMILES:
[H][C@]12CCc3cc(Cl)ccc3[C@]1([H])CCC(=O)N2C

References

1. Makrantonaki E, Zouboulis CC. Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes. Br J Dermatol. 2007 Mar;156(3):428-32. PubMed PMID: 17300229. 2. Issa S, Schnabel D, Feix M, Wolf L, Schaefer HE, Russell DW, Schweikert HU. Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1. J Clin Endocrinol Metab. 2002 Dec;87(12):5401-7. PubMed PMID: 12466325. 3. Guarna A, Occhiato EG, Scarpi D, Zorn C, Danza G, Comerci A, Mancina R, Serio M. Synthesis of 8-chloro-benzo[c]quinolizin-3-ones as potent and selective inhibitors of human steroid 5alpha-reductase 1. Bioorg Med Chem Lett. 2000 Feb 21;10(4):353-6. PubMed PMID: 10714498. 4. Farid NA, Coleman NL. High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY191704, a human type 1 5 alpha-reductase inhibitor, in plasma. J Chromatogr B Biomed Sci Appl. 1997 Mar 28;691(1):212-6. PubMed PMID: 9140778.