TargetMol

LSP4-2022

Product Code:
 
TAR-T27857
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27857-5mg5mg£850.00
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TAR-T27857-50mg50mg£1,661.00
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Quantity:
TAR-T27857-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.
CAS:
1413405-33-0
Formula:
C13H18NO8P
Molecular Weight:
347.26
Purity:
0.98
SMILES:
N[C@@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)cc1)C(O)=O

References

1. Wo?niak M, Go?embiowska K, Noworyta-Soko?owska K, Acher F, Cie?lik P, Kusek M, Tokarski K, Pilc A, Wiero?ska JM. Neurochemical and behavioral studies on the 5-HT(1A)-dependent antipsychotic action of the mGlu(4) receptor agonist LSP4-2022. Neuropharmacology. 2016 Jul 25. pii: S0028-3908(16)30278-7. doi: 10.1016/j.neuropharm.2016.06.025. [Epub ahead of print] PubMed PMID: 27465045. 2. Wo?niak M, Acher F, Marciniak M, Laso?-Tyburkiewicz M, Gruca P, Papp M, Pilc A, Wiero?ska JM. Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022. Curr Neuropharmacol. 2016;14(5):413-26. PubMed PMID: 26769224; PubMed Central PMCID: PMC4983756. 3. Podkowa K, Rze?niczek S, Marciniak M, Acher F, Pilc A, Pa?ucha-Poniewiera A. A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action. Neuropharmacology. 2015 Oct;97:338-45. doi: 10.1016/j.neuropharm.2015.05.039. PubMed PMID: 26074092.