TargetMol

Leucylleucine methyl ester

Product Code:
 
TAR-T27817
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27817-5mg5mg£850.00
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Quantity:
TAR-T27817-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27817-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Leucylleucine methyl ester is a drug potentially for the treatment of Graft-Versus-Host-Disease.
CAS:
13022-42-9
Formula:
C13H26N2O3
Molecular Weight:
258.362
Purity:
0.98
SMILES:
COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C

References

1. Hsieh MH, Varadi G, Flomenberg N, Korngold R. Leucyl-leucine methyl ester-treated haploidentical donor lymphocyte infusions can mediate graft-versus-leukemia activity with minimal graft-versus-host disease risk. Biol Blood Marrow Transplant. 2002;8(6):303-15. PubMed PMID: 12108916. 2. Ohlin M, Danielsson L, Carlsson R, Borrebaeck CA. The effect of leucyl-leucine methyl ester on proliferation and Ig secretion of EBV-transformed human B lymphocytes. Immunology. 1989 Apr;66(4):485-90. PubMed PMID: 2541070; PubMed Central PMCID: PMC1385146. 3. Mowat AM, Leck PA. Generalized toxicity of L-leucyl-leucine-methyl ester for lymphocyte functions. Immunology. 1990 Apr;69(4):564-9. PubMed PMID: 2335375; PubMed Central PMCID: PMC1385630. 4. Pechhold K, Kabelitz D. Human peripheral blood gamma delta T cells are uniformly sensitive to destruction by the lysosomotropic agents leucine methyl ester and leucyl leucine methyl ester. Eur J Immunol. 1993 Feb;23(2):562-5. PubMed PMID: 8436187.