TargetMol

LEI105

Product Code:
 
TAR-T27810
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27810-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
LEI105 is a potent, highly selective, and reversible inhibitor of DAGL-α and DAGL-β.
CAS:
1800327-36-9
Formula:
C25H24N2O2
Molecular Weight:
384.479
Purity:
0.98
SMILES:
Cc1ccc(cc1)-c1cnc2nc(oc2c1)C(=O)CCCCCc1ccccc1

References

1. Baggelaar MP, Chameau PJ, Kantae V, Hummel J, Hsu KL, Janssen F, van der Wel T, Soethoudt M, Deng H, den Dulk H, Allar? M, Florea BI, Di Marzo V, Wadman WJ, Kruse CG, Overkleeft HS, Hankemeier T, Werkman TR, Cravatt BF, van der Stelt M. Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons. J Am Chem Soc. 2015 Jul 15;137(27):8851-7. doi: 10.1021/jacs.5b04883. Epub 2015 Jul 1. PubMed PMID: 26083464; PubMed Central PMCID: PMC4773911.