TargetMol

L-775,606

Product Code:
 
TAR-T27782
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27782-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27782-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27782-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
L-775,606 is a selective agonist of 5-hydroxytryptamine 1D.
CAS:
188400-51-3
Formula:
C25H29FN6
Molecular Weight:
432.547
Purity:
0.98
SMILES:
Fc1cccc(CCN2CCN(CCCc3c[nH]c4ccc(cc34)-n3cnnc3)CC2)c1

References

1. Watt AP, Pike A, Morrison D. Determination of the collisionally activated dissociation of a substituted indole by orthogonal acceleration quadrupole time-of-flight mass spectrometry. J Am Soc Mass Spectrom. 2001 Nov;12(11):1145-52. PubMed PMID: 11720388. 2. Locker KL, Morrison D, Watt AP. Quantitative determination of L-775,606, a selective 5-hydroxytryptamine 1D agonist, in rat plasma using automated sample preparation and detection by liquid chromatography-tandem mass spectrometry. J Chromatogr B Biomed Sci Appl. 2001 Jan 5;750(1):13-23. PubMed PMID: 11204213. 3. Longmore J, Maguire JJ, MacLeod A, Street L, Schofield WN, Hill RG. Comparison of the vasoconstrictor effects of the selective 5-HT1D-receptor agonist L-775,606 with the mixed 5-HT1B/1D-receptor agonist sumatriptan and 5-HT in human isolated coronary artery. Br J Clin Pharmacol. 2000 Feb;49(2):126-31. PubMed PMID: 10671906; PubMed Central PMCID: PMC2014896. 4. Prueksaritanont T, Lu P, Gorham L, Sternfeld F, Vyas KP. Interspecies comparison and role of human cytochrome P450 and flavin-containing monooxygenase in hepatic metabolism of L-775,606, a potent 5-HT(1D) receptor agonist. Xenobiotica. 2000 Jan;30(1):47-59. PubMed PMID: 10659950.