TargetMol

KRP-199

Product Code:
 
TAR-T27748
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27748-5mg5mg£930.00
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Quantity:
TAR-T27748-50mg50mg£1,821.00
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Quantity:
TAR-T27748-100mg100mg£2,319.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KRP-199, a highly potent and selective antagonist for the AMPA receptors, exhibits good neuroprotective effects in vivo.
CAS:
221164-28-9
Formula:
C22H14F3N5O7
Molecular Weight:
517.377
Purity:
0.98
SMILES:
OC(=O)c1ccc(NC(=O)OCc2cn(cn2)-c2cc3nc(C(O)=O)c(=O)[nH]c3cc2C(F)(F)F)cc1

References

1. Takano Y, Shiga F, Asano J, Hori W, Fukuchi K, Anraku T, Uno T. Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPA receptor antagonists with good physicochemical properties. Bioorg Med Chem. 2006 Feb 1;14(3):776-92. Epub 2005 Oct 7. PubMed PMID: 16214358. 2. Takano Y, Shiga F, Asano J, Hori W, Anraku T, Uno T. Synthesis and AMPA receptor antagonistic activity of a novel 7-imidazolyl-6-trifluoromethyl quinoxalinecarboxylic acid with a substituted phenyl group and improved its good physicochemical properties by introduced CF3 group. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5107-11. PubMed PMID: 15380209.