TargetMol

Hyzetimibe

Product Code:
 
TAR-T27565
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T27565-5mg5mg£1,572.00
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Quantity:
TAR-T27565-50mg50mg£3,107.00
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Quantity:
TAR-T27565-100mg100mg£4,247.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Hyzetimibe, a cholesterol absorption blocker, is used potentially for the treatment of hypercholesterolemia.
CAS:
1266548-75-7
Formula:
C25H21F2NO3
Molecular Weight:
421.444
Purity:
0.98
SMILES:
OCC(=CC[C@@H]1[C@H](N(C1=O)c1ccc(F)cc1)c1ccc(O)cc1)c1ccc(F)cc1

References

1. Chen J, Lou H, Jiang B, Shao R, Ruan Z, Wang J. Simultaneous determination of hyzetimibe and its main active metabolite in plasma by LC-MS/MS and its application in PK study. Bioanalysis. 2015;7(15):1857-67. doi: 10.4155/bio.15.114. PubMed PMID: 26295987. 2. Ruan Z, Jiang B, Chen J, Zhang X, Lou H, Xiang M, Shao Q, Wang J. Pharmacokinetics, pharmacodynamics, safety, and tolerability of hyzetimibe (HS-25) in healthy Chinese subjects. J Clin Pharmacol. 2014 Oct;54(10):1144-52. doi: 10.1002/jcph.310. Epub 2014 Apr 21. PubMed PMID: 24752831.