TargetMol

Clovoxamine fumarate

Product Code:
 
TAR-T27047
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27047-5mg5mg£850.00
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TAR-T27047-50mg50mg£1,661.00
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TAR-T27047-100mg100mg£2,079.00
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Further Information

Bioactivity:
Clovoxamine is a nontricyclic antidepressant and has a dual action in blocking the reuptake of both noradrenaline and serotonin. Clovoxamine induces a decrease in the functional beta-adrenergic receptor coupled c-AMP response. Clovoxamine has little affinity for muscarinic, histaminergic, serotonergic and adrenergic binding sites.
CAS:
54739-19-4
Formula:
C18H25ClN2O6
Molecular Weight:
400.86
Purity:
0.98
SMILES:
OC(=O)C=CC(O)=O.COCCCCC(=N/OCCN)c1ccc(Cl)cc1

References

1. Jesinger DK, Gostick N. Anxiety neurosis in general practice. A double-blind comparative study of diazepam and clovoxamine, a novel inhibitor of noradrenaline and serotonin reuptake. Int Clin Psychopharmacol. 1989 Oct;4(4):301-11. PubMed PMID: 2691573. 2. Ochs HR, Greenblatt DJ, Verburg-Ochs B, Labedski L. Chronic treatment with fluvoxamine, clovoxamine, and placebo: interaction with digoxin and effects on sleep and alertness. J Clin Pharmacol. 1989 Jan;29(1):91-5. PubMed PMID: 2496149. 3. Saletu B, Gr?nberger J, Rajna P, Karobath M. Clovoxamine and fluvoxamine-2 biogenic amine re-uptake inhibiting antidepressants: quantitative EEG, psychometric and pharmacokinetic studies in man. J Neural Transm. 1980;49(1-2):63-86. PubMed PMID: 6777458. 4. Bradford LD, Tulp MT, Schipper J. Biochemical effects in rats after acute and long-term treatment with clovoxamine. Arch Int Pharmacodyn Ther. 1987 Jun;287(2):188-202. PubMed PMID: 2820327.