TargetMol

Tranilast

Product Code:
 
TAR-T2690
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2690-5mg5mg£101.00
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Quantity:
TAR-T2690-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T2690-10mg10mg£111.00
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TAR-T2690-25mg25mg£119.00
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TAR-T2690-100mg100mg£168.00
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Quantity:
TAR-T2690-200mg200mg£225.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
CAS:
53902-12-8
Formula:
C18H17NO5
Molecular Weight:
327.33
Pathway:
GPCR/G Protein; Immunology/Inflammation; Endocrinology/Hormones
Purity:
0.9957
SMILES:
COc1c(OC)cc(C=CC(Nc2c(C(O)=O)cccc2)=O)cc1
Target:
RAAS; Prostaglandin Receptor

References

1. Suzawa H, et al. Jpn J Pharmacol, 1992, 60(2), 91-96. 2. Suzawa H, et al. Jpn J Pharmacol, 1992, 60(2), 85-90. 3. Miyazawa K, et al. Atherosclerosis, 1995, 118(2), 213-221. 4. Martin J, et al. Cardiovasc Res, 2005, 65(3), 694-701. 5. Shiota N, et al. Circulation, 1999, 99(8), 1084-1090. 6. Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathway of PI3K/Akt/mTOR in esophageal squamous cell carcinoma[J]. 2020 7. Huang R, Wang F, Yang Y, et al. Recurrent activations of transient receptor potential vanilloid?1 and vanilloid?4 promote cellular proliferation and migration in esophageal squamous cell carcinoma cells[J]. FEBS open bio. 2019 Jan 18;9(2):206-225. 8. Liu J, Zhao Z, Wen J, et al. TNF-? differently regulates TRPV2 and TRPV4 channels in human dental pulp cells[J]. International endodontic journal. 2019. 9. Weiqiang H, Longshan Z, Mi Y, et al. Cancer-Associated Fibroblasts Promote the Survival of Irradiated Nasopharyngeal Carcinoma Cells via the NF-?B Pathway[J]. Journal of Experimental & Clinical Cancer Research. 2020