TargetMol

BRD2879

Product Code:
 
TAR-T26898
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26898-5mg5mg£1,733.00
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Quantity:
TAR-T26898-50mg50mg£3,428.00
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Quantity:
TAR-T26898-100mg100mg£4,729.00
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This product comes from: United States.
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Further Information

Bioactivity:
BRD2879 is a potent and cell-active inhibitor of IDH1-R132H (IC50 = 50 nM).
CAS:
1304750-47-7
Formula:
C30H38FN3O5S
Molecular Weight:
571.71
Purity:
0.98
SMILES:
C[C@@H](CO)N1C[C@@H](C)[C@H](CN(C)C(=O)NC2CCCCC2)Oc2cc(ccc2S1(=O)=O)C#Cc1cccc(F)c1

References

1. Discovery of 8-Membered Ring Sulfonamides as Inhibitors of Oncogenic Mutant Isocitrate Dehydrogenase 1 Jason M. Law, Sebastian C. Stark, Ke Liu, Norah E. Liang, Mahmud M. Hussain, Matthias Leiendecker, Daisuke Ito, Oscar Verho, Andrew M. Stern, Stephen E. Johnston, Yan-Ling Zhang, Gavin P. Dunn, Alykhan F. Shamji, and Stuart L. Schreiber Publication Date (Web): August 18, 2016 (Letter) doi: 10.1021/acsmedchemlett.6b00264