TargetMol

BMS-902483

Product Code:
 
TAR-T26862
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26862-5mg5mg£850.00
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TAR-T26862-50mg50mg£1,661.00
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Quantity:
TAR-T26862-100mg100mg£2,079.00
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Further Information

Bioactivity:
BMS-902483 is a potent α7 partial agonist. BMS-902483 improved cognition in preclinical rodent models. BMS-902483 showed FLIR α7 EC50=9.3nM; α7 Electrophysiology, rat; Area EC50 = 140 nM; Peak, Area (Ymax %) = 40, 54. 5-HT3A IC50 = 480 nm.
CAS:
1192810-88-0
Formula:
C18H20N4O
Molecular Weight:
308.385
Purity:
0.98
SMILES:
C1N=C(Nc2cc3ccccc3cn2)O[C@]11CN2CC[C@H]1CC2

References

1. Design and Synthesis of a New Series of 4-Heteroarylamino-1?-azaspiro[oxazole-5,3?-bicyclo[2.2.2]octanes as ?7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure?Activity Relationship James CookF. MacorRichard E. Olson Publication Date (Web): November 18, 2016 (Article) doi: 10.1021/acs.jmedchem.6b01506