TargetMol

AC-186

Product Code:
 
TAR-T26537
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26537-5mg5mg£850.00
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Further Information

Bioactivity:
AC-186 is a selective nonsteroidal estrogen receptor agonist.
CAS:
1421854-16-1
Formula:
C18H17F3O
Molecular Weight:
306.328
Purity:
0.98
SMILES:
Oc1ccc(cc1)C1(CCC(F)(F)CC1)c1ccccc1F

References

1. Shimada M, Kigawa J, Nishimura R, Hiura M, Hatae M, Takehara K, Sato A, Kurachi H, Mizunuma H, Sugiyama T. Comparison of the outcome between cervical adenocarcinoma and squamous cell carcinoma patients with adjuvant radiotherapy after radical surgery: SGSG/TGCU Intergroup Surveillance. J Clin Oncol. 2009 May 20;27(15_suppl):5585. PubMed PMID: 27962392. 2. Ma JN, McFarland K, Olsson R, Burstein ES. Estrogen Receptor Beta Selective Agonists as Agents to Treat Chemotherapeutic-Induced Neuropathic Pain. ACS Chem Neurosci. 2016 Sep 21;7(9):1180-7. doi: 10.1021/acschemneuro.6b00183. PubMed PMID: 27456785. 3. Price EW, Orvig C. Matching chelators to radiometals for radiopharmaceuticals. Chem Soc Rev. 2014 Jan 7;43(1):260-90. doi: 10.1039/c3cs60304k. Review. PubMed PMID: 24173525. 4. George S, Petit GH, Gouras GK, Brundin P, Olsson R. Nonsteroidal selective androgen receptor modulators and selective estrogen receptor ? agonists moderate cognitive deficits and amyloid-? levels in a mouse model of Alzheimer's disease. ACS Chem Neurosci. 2013 Dec 18;4(12):1537-48. doi: 10.1021/cn400133s. PubMed PMID: 24020966; PubMed Central PMCID: PMC3867967.