TargetMol

AA-CW236

Product Code:
 
TAR-T26496
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26496-5mg5mg£850.00
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Quantity:
TAR-T26496-50mg50mg£1,661.00
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Quantity:
TAR-T26496-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).
CAS:
1869921-96-9
Formula:
C17H16ClF3N4O2
Molecular Weight:
400.79
Purity:
0.98
SMILES:
Cc1noc(C)c1CCn1nnc(c1CCl)-c1ccc(OC(F)(F)F)cc1

References

1. Wang C, Abegg D, Hoch DG, Adibekian A. Chemoproteomics-Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT. Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2911-5. doi: 10.1002/anie.201511301. Epub 2016 Jan 22. PubMed PMID: 26798972.