TargetMol

AA 2379

Product Code:
 
TAR-T26491
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26491-5mg5mg£850.00
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TAR-T26491-50mg50mg£1,661.00
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Quantity:
TAR-T26491-100mg100mg£2,079.00
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Further Information

Bioactivity:
AA 2379, an anti inflammatory agent, inhibits the vascular permeability induced by histamine, serotonin, and bradykinin. It also has some analgesic activity.
CAS:
103446-98-6
Formula:
C15H23N5O4
Molecular Weight:
337.38
Purity:
0.98
SMILES:
CCCCn1c2nn(C(=O)OC)c(NC)c2c(=O)n(CCC)c1=O

References

1. Makino H, Saijo T, Maki Y. Inhibitory effects of methyl 7-butyl-4,5,6,7-tetrahydro-3-methylamino-4,6-dioxo-5-propyl- 2H-pyrazolo[3,4-d]pyrimidine-2-carboxylate (AA-2379) on lysosomal enzyme and arachidonic acid release from rat polymorphonuclear leukocytes and its mode of action. Agents Actions. 1989 Nov;28(3-4):248-55. PubMed PMID: 2556899. 2. Makino H, Naka T, Saijo T, Maki Y. Inhibitory effect of methyl 7-butyl-4,5,6,7-tetrahydro-3-methylamino-4,6-dioxo-5-propyl-2H-pyrazol o[3, 4-d]pyrimidine-2-carboxylate (AA-2379) on type III allergic (Arthus) reaction. Agents Actions. 1988 Dec;25(3-4):326-35. PubMed PMID: 2975457. 3. Makino H, Kuzuna S, Naka T, Saijo T, Maki Y. Antiinflammatory, analgesic, and antipyretic activities of methyl 7-butyl-4,5,6,7-tetrahydro-3-methylamino-4,6-dioxo-5-propyl-2H-pyrazol o[3, 4-d]pyrimidine-2-carboxylate (AA-2379), a novel non-acidic agent. Agents Actions. 1988 Dec;25(3-4):385-93. PubMed PMID: 3265269.