TargetMol

A 30312

Product Code:
 
TAR-T26413
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26413-5mg5mg£850.00
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Quantity:
TAR-T26413-50mg50mg£1,661.00
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Quantity:
TAR-T26413-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
A 30312 is a fused indole, which overcomes multidrug resistance in P388/Adr cells in vitro. It potentiates the cytotoxicity of the antitumor drugs Adriamycin, vincristine and vinblastine in multidrug-resistant cells with no effect on drug-sensitive parent P388 cells.
CAS:
144092-65-9
Formula:
C19H21ClN2O
Molecular Weight:
328.84
Purity:
0.98
SMILES:
Cl.COc1ccc2[nH]c3CCN(Cc4ccccc4)Cc3c2c1

References

1. Kadam S, Maus M, Poddig J, Schmidt S, Rasmussen R, Novosad E, Plattner J, McAlpine J. Reversal of multidrug resistance by two novel indole derivatives. Cancer Res. 1992 Sep 1;52(17):4735-40. PubMed PMID: 1355008.