TargetMol

A 1110U

Product Code:
 
TAR-T26402
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26402-5mg5mg£850.00
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Quantity:
TAR-T26402-50mg50mg£1,661.00
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Quantity:
TAR-T26402-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
A 1110U is an inactivator of herpes simplex virus ribonucloetide reductases.
CAS:
96860-23-0
Formula:
C11H16N6S2
Molecular Weight:
296.41
Purity:
0.98
SMILES:
CN(C)C(=S)NNC(=S)NN=C(/C)c1ccccn1

References

1. Porter DJ, Harrington JA, Spector T. Herpes simplex virus type 1 ribonucleotide reductase: selective and synergistic inactivation by A1110U and its iron complex. Biochem Pharmacol. 1990 Feb 15;39(4):639-46. PubMed PMID: 2154988. 2. Ellis MN, Lobe DC, Spector T. Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses. Antimicrob Agents Chemother. 1989 Oct;33(10):1691-6. PubMed PMID: 2556074; PubMed Central PMCID: PMC172739. 3. Spector T, Harrington JA, Porter DJ. Herpes and human ribonucleotide reductases. Inhibition by 2-acetylpyridine 5-[(2-chloroanilino)-thiocarbonyl]-thiocarbonohydrazone (348U87). Biochem Pharmacol. 1991 Jun 21;42(1):91-6. PubMed PMID: 1648925. 4. Spector T, Harrington JA, Morrison RW Jr, Lambe CU, Nelson DJ, Averett DR, Biron K, Furman PA. 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir. Proc Natl Acad Sci U S A. 1989 Feb;86(3):1051-5. PubMed PMID: 2536930; PubMed Central PMCID: PMC286619.