TargetMol

KUC-7322

Product Code:
 
TAR-T26094
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26094-5mg5mg£1,010.00
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TAR-T26094-50mg50mg£1,982.00
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Quantity:
TAR-T26094-100mg100mg£2,560.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Ritobegron is used as a selective β3-adrenoceptor agonist and the prodrug of the active compound, KUC-7322.
CAS:
255734-04-4
Formula:
C21H27NO5
Molecular Weight:
373.449
Purity:
0.98
SMILES:
C[C@H](NCCc1cc(C)c(OCC(O)=O)cc1C)[C@H](O)c1ccc(O)cc1

References

1. Abe Y, Ota E, Harada H, Kanbe H, Kojima Y, Kanazawa T, Endo T, Murakami M, Kobayashi M. Species differences in the metabolism of ritobegron in vitro and assessment of potential interactions with transporters and cytochrome P450 enzymes. Pharmazie. 2015 Jan;70(1):38-46. PubMed PMID: 25975097. 2. Abe Y, Ota E, Endo T, Murakami M, Kobayashi M. Absorption, disposition, metabolism, and excretion of ritobegron (KUC-7483), a novel selective ?3-adrenoceptor agonist, in rats. Pharmazie. 2014 Dec;69(12):881-8. PubMed PMID: 25951660. 3. Maruyama I, Yonekubo S, Tatemichi S, Maruyama K, Hoyano Y, Yamazaki Y, Kusama H. Effects of ritobegron (KUC-7483), a novel ?3-adrenoceptor agonist, on both rat bladder function following partial bladder outlet obstruction and on rat salivary secretion: a comparison with the effects of tolterodine. J Smooth Muscle Res. 2012;48(5-6):115-24. PubMed PMID: 23538508. 4. Abe Y, Nakano Y, Kanazawa T, Furihata T, Endo T, Kobayashi M. Investigation of Drug-Drug Interactions Between Ritobegron, a Selective ?3 -Adrenoceptor Agonist, With Probenecid in Healthy Men. Clin Pharmacol Drug Dev. 2016 May;5(3):201-7. doi: 10.1002/cpdd.212. Epub 2015 Sep 29. PubMed PMID: 27163499.