TargetMol

Masitinib

Product Code:
 
TAR-T2609
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2609-5mg5mg£95.00
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TAR-T2609-10mg10mg£109.00
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TAR-T2609-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T2609-50mg50mg£143.00
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TAR-T2609-100mg100mg£201.00
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TAR-T2609-200mg200mg£273.00
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This product comes from: United States.
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Further Information

Bioactivity:
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
CAS:
790299-79-5
Formula:
C28H30N6OS
Molecular Weight:
498.65
Pathway:
Tyrosine Kinase/Adaptors; Apoptosis; Angiogenesis; Cytoskeletal Signaling
Purity:
0.9991
SMILES:
CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1
Target:
Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck

References

1. Dubreuil P, et al. PLoS One, 2009, 4(9), e7258. 2. Lawrence J, et al. Vet Comp Oncol, 2011, doi: 10.1111/j.1476-5829.2011.200291.x. 3. Hahn KA, et al. J Vet Intern Med, 2008, 22(6), 1301-1309. 4. Humbert M, et al. PLoS One, 2010, 5(3), e9430.