TargetMol

Promothiocin A

Product Code:
 
TAR-T25991
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25991-5mg5mg£850.00
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Further Information

Bioactivity:
Promothiocin A is an antibiotic.
CAS:
156737-05-2
Formula:
C36H37N11O8S2
Molecular Weight:
815.88
Purity:
0.98
SMILES:
CC(C)[C@@H]1NC(=O)c2csc(n2)-c2ccc(nc2-c2nc(oc2C)[C@H](C)NC(=O)c2csc(n2)[C@H](C)NC(=O)c2nc(CNC1=O)oc2C)C(=O)NC(=C)C(N)=O

References

1. Habazettl J, Allan M, Jensen PR, Sass HJ, Thompson CJ, Grzesiek S. Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5498-507. doi: 10.1073/pnas.1412070111. Epub 2014 Dec 8. PubMed PMID: 25489067; PubMed Central PMCID: PMC4280590. 2. Takagi M, Motohashi K, Nagai A, Hashimoto J, Shin-Ya K. JBIR-83 and JBIR-84, new promothiocin derivatives, isolated from Streptomyces sp. RI19. J Antibiot (Tokyo). 2010 Jul;63(7):405-8. doi: 10.1038/ja.2010.66. Epub 2010 Jun 16. PubMed PMID: 20551986. 3. Yun BS, Hidaka T, Furihata K, Seto H. Promothiocins A and B novel thiopeptides with a tipA promoter inducing activity produced by Streptomyces sp. SF2741. J Antibiot (Tokyo). 1994 Apr;47(4):510-4. PubMed PMID: 8195055.