TargetMol

NSC-689857

Product Code:
 
TAR-T25889
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T25889-50mg50mg£815.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25889-100mg100mg£1,259.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NSC-689857 is an inhibitor that acts in the Skp2-Cks1 protein-protein interaction and p27Kip1 ubiquitination in vitro.
CAS:
241127-79-7
Formula:
C25H29NO4
Molecular Weight:
407.51
Purity:
0.98
SMILES:
Oc1ccc(O)c(CNc2ccc(cc2)C(=O)OCC23CC4CC(CC(C4)C2)C3)c1

References

1. Ungermannova D, Lee J, Zhang G, Dallmann HG, McHenry CS, Liu X. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1. J Biomol Screen. 2013 Sep;18(8):910-20. doi: 10.1177/1087057113485789. Epub 2013 Apr 15. PubMed PMID: 23589337; PubMed Central PMCID: PMC4168015.