TargetMol

Lorcainide hydrochloride

Product Code:
 
TAR-T25757
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25757-5mg5mg£850.00
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TAR-T25757-50mg50mg£1,661.00
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TAR-T25757-100mg100mg£2,079.00
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Further Information

Bioactivity:
Lorcainide hydrochloride is an antiarrhythmic drug with local anesthetic activity. The antiarrhythmic actions of lorcainide are mediated by an impairment of fast sodium conductance. Lorcainide appears effective in suppressing reentry phenomena and ectopic pacemaker activity, especially in the ventricles.
CAS:
58934-46-6
Formula:
C22H28Cl2N2O
Molecular Weight:
407.38
Purity:
0.98
SMILES:
Cl.CC(C)N1CCC(CC1)N(C(=O)Cc1ccccc1)c1ccc(Cl)cc1

References

1. Luo X, Zeng FD. [HPLC method for determination of lorcainide hydrochloride in human serum]. Yao Xue Xue Bao. 1995;30(8):605-9. Chinese. PubMed PMID: 8571780. 2. Somberg JC, Laux B, Wynn J, Keefe D, Miura DS. Lorcainide therapy in a cardiac arrest population. Am Heart J. 1986 Apr;111(4):648-53. PubMed PMID: 3953387. 3. Lauwers WF, Meuldermans WE, Bracke JO. Mass spectral investigation of the metabolites of lorcainide in man. Eur J Drug Metab Pharmacokinet. 1983 Oct-Dec;8(4):351-62. PubMed PMID: 6673972. 4. Shita A, Bernard R, Mostinckx R, Debacker M. Haemodynamic reactions after intravenous injection of lorcainide hydrochloride in acute myocardial infarction. Eur J Cardiol. 1981;12(5):237-42. PubMed PMID: 7250167.