TargetMol

Linotroban

Product Code:
 
TAR-T25741
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25741-5mg5mg£790.00
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TAR-T25741-50mg50mg£1,661.00
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Quantity:
TAR-T25741-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Linotroban is a thromboxane A2 receptor antagonist.
CAS:
120824-08-0
Formula:
C14H15NO5S2
Molecular Weight:
341.4
Purity:
0.98
SMILES:
OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)s1

Documents

References

1. Sadjak A, Supanz S, Fellier H. Determination of efficacy of linotroban by inducing a reduction of renal inulin/para-aminohippuric acid clearances with the thromboxane A2 mimetic U-46619 in the conscious female rat. Arzneimittelforschung. 2000 Sep;50(9):816-20. PubMed PMID: 11050698. 2. Dorner GT, Pehamberger H, Kornek G, Steger G, M?ller M, Wolzt M, Kletter K, James P, Breiteneder H, Eichler HG, Bl?chl-Daum B. Cisplatin-induced renal effects and thromboxane A2 receptor blockade. Eur J Clin Invest. 1997 Oct;27(10):836-9. PubMed PMID: 9373762. 3. Supanz S, Sadjak A, Fellier H, Eidenberger T. Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. Arzneimittelforschung. 1997 Sep;47(9):1026-30. PubMed PMID: 9342416. 4. Li GA, Wang X, Meng X, Lin YB, Li X, Liu XJ. [Design, synthesis of novel N, N'-bis-(halogenophenyl)-4- methoxybenzene-1, 3-disulfonamides and evaluation of their anti-platelet aggregation activity]. Yao Xue Xue Bao. 2015 Feb;50(2):185-90. Chinese. PubMed PMID: 25975026.