TargetMol

Leucine thiorphan

Product Code:
 
TAR-T25676
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25676-5mg5mg£850.00
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Quantity:
TAR-T25676-50mg50mg£1,661.00
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Quantity:
TAR-T25676-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Leucine thiorphan is an inhibitor of enkephalinase.
CAS:
80970-04-3
Formula:
C16H23NO3S
Molecular Weight:
309.42
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)C(CS)Cc1ccccc1)C(O)=O

References

1. Di Maria GU, Katayama M, Borson DB, Nadel JA. Neutral endopeptidase modulates endothelin-1-induced airway smooth muscle contraction in guinea-pig trachea. Regul Pept. 1992 Jun 11;39(2-3):137-45. PubMed PMID: 1438968. 2. Kohrogi H, Nadel JA, Malfroy B, Gorman C, Bridenbaugh R, Patton JS, Borson DB. Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. J Clin Invest. 1989 Sep;84(3):781-6. PubMed PMID: 2474575; PubMed Central PMCID: PMC329719. 3. Djokic TD, Nadel JA, Dusser DJ, Sekizawa K, Graf PD, Borson DB. Inhibitors of neutral endopeptidase potentiate electrically and capsaicin-induced noncholinergic contraction in guinea pig bronchi. J Pharmacol Exp Ther. 1989 Jan;248(1):7-11. PubMed PMID: 2464061. 4. Djokic TD, Sekizawa K, Borson DB, Nadel JA. Neutral endopeptidase inhibitors potentiate substance P-induced contraction in gut smooth muscle. Am J Physiol. 1989 Jan;256(1 Pt 1):G39-43. PubMed PMID: 2463769.