TargetMol

IRL-3630

Product Code:
 
TAR-T25541
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25541-5mg5mg£850.00
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Further Information

Bioactivity:
IRL 3460 is an enantiomer.
CAS:
173189-01-0
Formula:
C31H40N4O6S
Molecular Weight:
596.74
Purity:
0.98
SMILES:
CCCCS(=O)(=O)N([C@@H](C(C)C)C(N)=O)C(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1

References

1. Sakaki J, Murata T, Yuumoto Y, Nakamura I, Hayakawa K. Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2247-52. PubMed PMID: 9873522. 2. Sakaki J, Murata T, Yuumoto Y, Nakamura I, Trueh T, Pitterna T, Iwasaki G, Oda K, Yamamura T, Hayakawa K. Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2241-6. PubMed PMID: 9873521. 3. Makatani M, Fujitani Y, Takimoto M, Oda K, Sasaki Y, Hori S, Inui T, Sakaki J, Okada T, Hoshiko K, Yamamura T. Effect of a novel bifunctional endothelin receptor antagonist, IRL 3630A, on guinea pig respiratory mechanics. Eur J Pharmacol. 2000 Oct 6;406(1):139-47. PubMed PMID: 11011045.