TargetMol

IMB-808

Product Code:
 
TAR-T25528
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T25528-100mg100mgEnquire
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Further Information

Bioactivity:
IMB-808 is an effective partial dual agonist of liver X receptor α and β (LXRα/β) that promotes the expression of genes related to reverse cholesterol transport (including ABCA1 and ABCG1).
CAS:
870768-70-0
Formula:
C18H15F3N2O4
Molecular Weight:
380.323
Purity:
0.98
SMILES:
CN(CC(=O)Nc1ccc(F)c(F)c1F)C(=O)c1ccc2OCCOc2c1

References

1. Li N, Wang X, Xu Y, Lin Y, Zhu N, Liu P, Lu D, Si S. Identification of a Novel Liver X Receptor Agonist that Regulates the Expression of Key Cholesterol Homeostasis Genes with Distinct Pharmacological Characteristics. Mol Pharmacol. 2017 Apr;91(4):264-276. doi: 10.1124/mol.116.105213. Epub 2017 Jan 13. PubMed PMID: 28087808.