TargetMol

Ganoderiol B

Product Code:
 
TAR-T25445
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T25445-5mg5mg£850.00
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Further Information

Bioactivity:
Ganoderiol B is a moderately active HIV-1 PR inhibitor (IC50: 0.17-0.23 mM).
CAS:
106518-62-1
Formula:
C30H46O4
Molecular Weight:
470.694
Purity:
0.98
SMILES:
[H][C@@]12CC=C3C(=CC[C@]4(C)[C@H](C[C@H](O)[C@@]34C)[C@H](C)CCC=C(CO)CO)[C@@]1(C)CCC(=O)C2(C)C

References

1. el-Mekkawy S, Meselhy MR, Nakamura N, Tezuka Y, Hattori M, Kakiuchi N, Shimotohno K, Kawahata T, Otake T. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry. 1998 Nov;49(6):1651-7. PubMed PMID: 9862140. 2. Liu JQ, Wang CF, Li Y, Luo HR, Qiu MH. Isolation and bioactivity evaluation of terpenoids from the medicinal fungus Ganoderma sinense. Planta Med. 2012 Mar;78(4):368-76. doi: 10.1055/s-0031-1280441. Epub 2011 Dec 12. PubMed PMID: 22161763. 3. Qiao Y, Zhang XM, Qiu MH. Two novel lanostane triterpenoids from Ganoderma sinense. Molecules. 2007 Aug 23;12(8):2038-46. PubMed PMID: 17960104. 4. Min BS, Gao JJ, Hattori M, Lee HK, Kim YH. Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. Planta Med. 2001 Dec;67(9):811-4. PubMed PMID: 11745016.