TargetMol

FR20

Product Code:
 
TAR-T25440
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25440-5mg5mg£850.00
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Quantity:
TAR-T25440-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25440-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.
CAS:
570373-45-4
Formula:
C31H25Cl2N3O2
Molecular Weight:
542.46
Purity:
0.98
SMILES:
CCCc1nc2ccc(NC(=O)c3ccccc3Cl)cc2c(=O)n1Cc1ccc(cc1)-c1cccc(Cl)c1

References

1. da Silva GP, Fernandes DC, Vigliano MV, da Fonseca EN, Santos SV, Marques PR, Justo MD, Sabino KC, Coelho MG. Flavonoid-enriched fraction from Echinodorus macrophyllus aqueous extract exhibits high in-vitro and in-vivo anti-inflammatory activity. J Pharm Pharmacol. 2016 Dec;68(12):1584-1596. doi: 10.1111/jphp.12620. Epub 2016 Oct 10. PubMed PMID: 27726146. 2. Dienel GA, Cruz NF, Ball K, Popp D, Gokden M, Baron S, Wright D, Wenger GR. Behavioral training increases local astrocytic metabolic activity but does not alter outcome of mild transient ischemia. Brain Res. 2003 Jan 31;961(2):201-12. PubMed PMID: 12531487. 3. Wilson RD, Islam MS. Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes. Pharmacol Rep. 2012;64(1):129-39. PubMed PMID: 22580529. 4. Randall PA, Nunes EJ, Janniere SL, Stopper CM, Farrar AM, Sager TN, Baqi Y, Hockemeyer J, M?ller CE, Salamone JD. Stimulant effects of adenosine antagonists on operant behavior: differential actions of selective A2A and A1 antagonists. Psychopharmacology (Berl). 2011 Jul;216(2):173-86. doi: 10.1007/s00213-011-2198-3. Epub 2011 Feb 24. PubMed PMID: 21347642; PubMed Central PMCID: PMC3522121.