TargetMol

Enprostil

Product Code:
 
TAR-T25375
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Enprostil is a synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has efficient and safe in the therapy of gastroduodenal ulcers.
CAS:
73121-56-9
Formula:
C23H28O6
Molecular Weight:
400.471
Purity:
0.98
SMILES:
COC(=O)CCC=C=CCC1C(C=CC(O)COc2ccccc2)C(O)CC1=O

References

1. Morgan AG, Pacsoo C, Taylor P, McAdam WA. A comparison between enprostil and ranitidine in the management of gastric ulceration. Aliment Pharmacol Ther. 1990 Dec;4(6):635-41. PubMed PMID: 2129650. 2. Omura N, Kashiwagi H, Aoki T, Omura K, Fukuchi Y. Effects of enprostil on gastric endocrine secretion during chronic administration of lansoprazole. J Gastroenterol. 1997 Dec;32(6):740-6. PubMed PMID: 9430011. 3. Bardhan KD, Walker R, Hinchliffe RF, Bose K, Morris P, Thompson M, Miller JP, Toivanen E, Thompson RP, Patrier P, et al. Gastric ulcer healing: a comparison of enprostil versus ranitidine. J Clin Gastroenterol. 1991 Apr;13(2):157-62. PubMed PMID: 1903407. 4. Lartigue S, Corrion F, Bernades P, Bonfils S, Chevalier T, Laverdant C, Mignon M, Minaire Y, Pariente A, Vicari F, et al. [Effect of enprostil on the healing and the recurrence of duodenal ulcer. Comparison with ranitidine]. Gastroenterol Clin Biol. 1994;18(6-7):617-22. French. PubMed PMID: 7875419.