TargetMol

Echinoside B

Product Code:
 
TAR-T25359
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T25359-5mg5mg£850.00
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Further Information

Bioactivity:
Echinoside B shows anti-tumor activities in vitro and vivo.
CAS:
75410-52-5
Formula:
C41H66NaO17S
Molecular Weight:
886.01
Purity:
0.98
SMILES:
[Na+].CC(C)CCCC(C)(O)C1(O)CC[C]23(C)OC(=O)C12C(O)C=C1C3CCC2C(C)(C)C(CCC12C)OC1OCC(OS([O-])(=O)=O)C(O)C1OC1OC(C)C(O)C(O)C1O

References

1. Zhao Q, Xue Y, Wang JF, Li H, Long TT, Li Z, Wang YM, Dong P, Xue CH. In vitro and in vivo anti-tumour activities of echinoside A and ds-echinoside A from Pearsonothuria graeffei. J Sci Food Agric. 2012 Mar 15;92(4):965-74. doi: 10.1002/jsfa.4678. Epub 2011 Oct 19. PubMed PMID: 22012678. 2. Melek FR, Tadros MM, Yousif F, Selim MA, Hassan MH. Screening of marine extracts for schistosomicidal activity in vitro. Isolation of the triterpene glycosides echinosides A and B with potential activity from the Sea Cucumbers Actinopyga echinites and Holothuria polii. Pharm Biol. 2012 Apr;50(4):490-6. doi: 10.3109/13880209.2011.615842. Epub 2011 Dec 2. PubMed PMID: 22136393. 3. Yamasaki Y, Ito K, Enomoto Y, Sutko JL. Alterations by saponins of passive Ca2+ permeability and Na+-Ca2+ exchange activity of canine cardiac sarcolemmal vesicles. Biochim Biophys Acta. 1987 Mar 12;897(3):481-7. PubMed PMID: 3814597. 4. Enomoto Y, Ito K, Kawagoe Y, Morio Y, Yamasaki Y. Positive inotropic action of saponins on isolated atrial and papillary muscles from the guinea-pig. Br J Pharmacol. 1986 May;88(1):259-67. PubMed PMID: 3708218; PubMed Central PMCID: PMC1917120.