TargetMol

Diprotin A

Product Code:
 
TAR-T25340
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25340-5mg5mg£103.00
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TAR-T25340-10mg10mg£116.00
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TAR-T25340-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T25340-25mg25mg£148.00
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TAR-T25340-50mg50mg£197.00
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TAR-T25340-100mg100mg£260.00
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This product comes from: United States.
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Further Information

Bioactivity:
Diprotin A (Ile-Pro-Ile) is a dipeptidyl peptidase IV (DPP-IV) inhibitor.
CAS:
90614-48-5
Formula:
C17H31N3O4
Molecular Weight:
341.452
Pathway:
Proteases/Proteasome
Purity:
0.9929
SMILES:
CC[C@H](C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(O)=O
Target:
DPP-4

References

1. Lee CS, et al. Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation. Sci Rep. 2016 Jul 6;6:29393. 2. Chakraborty C, Hsu MJ, Agoramoorthy G. Understanding the molecular dynamics of type-2 diabetes drug target DPP-4 and its interaction with Sitagliptin and inhibitor Diprotin-A. Cell Biochem Biophys. 2014 Nov;70(2):907-22. doi: 10.1007/s12013-014-9998-0. PubMed PMID: 24809328. 3. Zhang D, Huang W, Dai B, Zhao T, Ashraf A, Millard RW, Ashraf M, Wang Y. Genetically manipulated progenitor cell sheet with diprotin A improves myocardial function and repair of infarcted hearts. Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1339-47. doi: 10.1152/ajpheart.00592.2010. Epub 2010 Aug 27. PubMed PMID: 20802132; PubMed Central PMCID: PMC2993193. 4. Krupina NA, Khlebnikova NN. Omega-3 polyunsaturated fatty acids when administered to lactating rats modify the development of experimental anxiety-depressive state in the rat pups exposed to the dipeptidyl peptidase-IV inhibitor diprotin A on the second - third weeks after the birth. Patol Fiziol Eksp Ter. 2016 Oct-Dec;60(4):9-19. PubMed PMID: 29244917.