TargetMol

CL67

Product Code:
 
TAR-T25255
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25255-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25255-50mg50mg£1,661.00
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Quantity:
TAR-T25255-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.
CAS:
1401242-86-1
Formula:
C38H42N10O2
Molecular Weight:
670.822
Purity:
0.98
SMILES:
CCN(CC)CC(=O)Nc1cccc(c1)-n1cc(nn1)-c1ccc2ccc(cc2c1)-c1cn(nn1)-c1cccc(NC(=O)CN(CC)CC)c1

References

1. Welsh SJ, Dale AG, Lombardo CM, Valentine H, de la Fuente M, Schatzlein A, Neidle S. Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule. Sci Rep. 2013 Sep 30;3:2799. doi: 10.1038/srep02799. PubMed PMID: 24165797; PubMed Central PMCID: PMC3810677. 2. Ellenberg P, Edreira M, Lozano M, Scolaro L. Synthesis and expression of viral antigens in Vero cells persistently infected with Junin virus. Arch Virol. 2002 Aug;147(8):1543-57. PubMed PMID: 12181674. 3. Scolaro LA, Damonte EB. Glycoprotein-mediated biological properties of a host range mutant of Junin virus. Res Virol. 1997 Sep-Oct;148(5):323-31. PubMed PMID: 9403931. 4. Scolaro LA, Mersich SE, Damonte EB. Experimental infection of suckling mice with a host range mutant of Junin virus. J Med Virol. 1991 Aug;34(4):237-40. PubMed PMID: 1658215.