TargetMol

CHM-1-P-Na

Product Code:
 
TAR-T25245
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25245-5mg5mg£850.00
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TAR-T25245-50mg50mg£1,661.00
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Quantity:
TAR-T25245-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.
CAS:
1207854-61-2
Formula:
C16H10FNNaO6P
Molecular Weight:
385.219
Purity:
0.98
SMILES:
[Na+].OP([O-])(=O)Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F

References

1. Chou LC, Tsai MT, Hsu MH, Wang SH, Way TD, Huang CH, Lin HY, Qian K, Dong Y, Lee KH, Huang LJ, Kuo SC. Design, synthesis, and preclinical evaluation of new 5,6- (or 6,7-) disubstituted-2-(fluorophenyl)quinolin-4-one derivatives as potent antitumor agents. J Med Chem. 2010 Nov 25;53(22):8047-58. doi: 10.1021/jm100780c. Epub 2010 Oct 25. PubMed PMID: 20973552. 2. Chou LC, Chen CT, Lee JC, Way TD, Huang CH, Huang SM, Teng CM, Yamori T, Wu TS, Sun CM, Chien DS, Qian K, Morris-Natschke SL, Lee KH, Huang LJ, Kuo SC. Synthesis and preclinical evaluations of 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one monosodium phosphate (CHM-1-P-Na) as a potent antitumor agent. J Med Chem. 2010 Feb 25;53(4):1616-26. doi: 10.1021/jm901292j. PubMed PMID: 20102207.