TargetMol

Candicidin

Product Code:
 
TAR-T25202
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25202-5mg5mg£1,570.00
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  • Further Information
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Further Information

Bioactivity:
Candicidin is an antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topically in candidiasis. The antibiotic is composed of candicidins A, B, C, and D, of which D is the major component.
CAS:
1403-17-4
Formula:
C59H84N2O18
Molecular Weight:
1109.317
Purity:
0.98
SMILES:
CC(CC(C)C1OC(=O)CC(=O)CCCC(=O)CC(O)CC(O)CC(O)CC(=O)CC(O)C(C(O)CC(OC2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C=CC=CC=CC=CC=CC=CC=CC1C)C(O)=O)C(O)CC(=O)c1ccc(N)cc1

References

1. Szwarc K, Szczeblewski P, Sowi?ski P, Borowski E, Pawlak J. The stereostructure of candicidin D. J Antibiot (Tokyo). 2015 Aug;68(8):504-10. doi: 10.1038/ja.2015.17. Epub 2015 Feb 25. PubMed PMID: 25712395. 2. Zhang P, Zhao Z, Li H, Chen XL, Deng Z, Bai L, Pang X. Production of the antibiotic FR-008/candicidin in Streptomyces sp. FR-008 is co-regulated by two regulators, FscRI and FscRIV, from different transcription factor families. Microbiology. 2015 Mar;161(Pt 3):539-52. doi: 10.1099/mic.0.000033. Epub 2015 Jan 9. PubMed PMID: 25575546. 3. Lei X, Kong L, Zhang C, Liu Q, Yao F, Zhang W, Deng Z, You D. In vivo investigation of the substrate recognition capability and activity affecting amino acid residues of glycosyltransferase FscMI in the biosynthesis of candicidin. Mol Biosyst. 2013 Mar;9(3):422-30. doi: 10.1039/c2mb25464f. Epub 2013 Jan 17. PubMed PMID: 23324745. 4. Lei X, Kong L, Zhang C, You D, Deng Z. [Function of transporter genes fscTI and fscTII in the biosynthetic cluster of candicidin/FR-008]. Wei Sheng Wu Xue Bao. 2012 Dec 4;52(12):1458-66. Chinese. PubMed PMID: 23457795.