TargetMol

UBP714

Product Code:
 
TAR-T24919
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24919-5mg5mg£850.00
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TAR-T24919-50mg50mg£1,661.00
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Quantity:
TAR-T24919-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
UBP714 is a derivative of the NMDA receptor negative allosteric modulator UBP608. It also enhanced NMDAR mediated field EPSPs in the CA1 region of the hippocampus. UBP714 is a novel template for the development of potent and subunit selective NMDAR potentiators that may have therapeutic applicability in the therapy of patients with schizophrenia or cognitive deficits.
CAS:
773109-55-0
Formula:
C11H7BrO4
Molecular Weight:
283.077
Purity:
0.98
SMILES:
Cc1c(C(O)=O)c(=O)oc2ccc(Br)cc12

References

1. Irvine MW, Costa BM, Volianskis A, Fang G, Ceolin L, Collingridge GL, Monaghan DT, Jane DE. Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochem Int. 2012 Sep;61(4):593-600. doi: 10.1016/j.neuint.2011.12.020. Epub 2012 Jan 13. PubMed PMID: 22265875; PubMed Central PMCID: PMC3394894.