TargetMol

SMU-B

Product Code:
 
TAR-T24809
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24809-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24809-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24809-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SMU-B is a well-tolerated c-Met/ALK dual inhibitor.
CAS:
1253286-90-6
Formula:
C26H25Cl2FN4O2
Molecular Weight:
515.41
Purity:
0.98
SMILES:
C[C@@H](Oc1cc(cnc1N)-c1ccc2c(NC(=O)C22CCN(C)CC2)c1)c1c(Cl)ccc(F)c1Cl

References

1. Tian Y, Yu Y, Shen Y, Wan H, Chang S, Zhang T, Wan S, Zhang J. Molecular Simulation Studies on the Binding Selectivity of Type-I Inhibitors in the Complexes with ROS1 versus ALK. J Chem Inf Model. 2017 Apr 24;57(4):977-987. doi: 10.1021/acs.jcim.7b00019. Epub 2017 Mar 29. PubMed PMID: 28318251. 2. Li J, Wu N, Tian Y, Zhang J, Wu S. Aminopyridyl/Pyrazinyl Spiro[indoline-3,4'-piperidine]-2-ones As Highly Selective and Efficacious c-Met/ALK Inhibitors. ACS Med Chem Lett. 2013 Jul 12;4(8):806-10. doi: 10.1021/ml400203d. eCollection 2013 Aug 8. PubMed PMID: 24900750; PubMed Central PMCID: PMC4027565.